Human Amniotic Membrane Usage from Bench to Bedside in Congenital Defects and Wounds in Paediatric Surgery: A Systematic Review

Bench-to-bedside review: Inotropic drug therapy after adult cardiac surgery – a systematic literature review

Many adult patients require temporary inotropic support after cardiac surgery. We reviewed the literature systematically to establish, present and classify the evidence regarding choice of inotropic drugs. The available evidence, while limited in quality and scope, supports the following observations; although all beta-agonists can increase cardiac output, the best studied beta-agonist and the ...

Bench to bedside review

opium abuse and its problems in anesthesia practice: a review from bench to bedside

opium is a derivative of opium poppy; the species of plant which its extract is used for preparing opium. opium abuse is considered under drug dependency classification of psychiatric diseases and opium abusers have a number of major challenges before, during and after anesthesia for surgical operations (i.e. the perioperative period). this article reviews these clinical challenges during the p...

Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside

Immunotherapy has been used for years in many types of cancer therapy. Recently, cancer immunotherapy has focused on mechanisms which can enhance the development of cell-mediated immunity. Anticancer medications are administered to inhibit immunosuppressive factors such as nagalase enzyme, which is produced by neoplastic cells and destroys macrophage activating factor (Gc-MAF). Anti-neoplastics...

From bench to bedside

Because the microcirculation has emerged as an important reanimation target, appropriate methods to monitor the microcirculatory function are crucial. Several teams have now succeeded in crossing this bridge from bench to bedside, but the choice of the tissues of interest remains a debate. The potential accessible vascular beds that doctors could use in reanimation strategies and the relationsh...